Process for the preparation of azamacrocyclic or acyclic aminoph

Details Process for the preparation of azamacrocyclic or acyclic aminoph Process for the preparation of azamacrocyclic or acyclic aminoph

1993-05-06

1998-02-03

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540474, 540450, 540471, C07D25708, C07F 96524

Patent

active

057146047

ABSTRACT:
A novel process for the preparation of azamacrocyclic or acyclic aminophosphonate ester derivatives is disclosed. The process concerns the reaction of an appropriate azamacrocyclic or acyclic primary or secondary amine with trialkyl phosphite and paraformaldehyde.

REFERENCES:
patent: 5236695 (1993-08-01), Winchell et al.
patent: 5342936 (1994-08-01), Parker et al.
patent: 5385893 (1995-01-01), Kiefer
patent: 5606053 (1997-02-01), Prashad et al.
patent: 5630997 (1997-05-01), Sherry et al.
Maier, Phosphorus and Sulfur, (1987), vol. 33 (1-2), pp. 41-52.
Natcher, Synthesis, vol. 12, (1987), pp. 1079-1084.
Maier et al, Chemical Abstract 109(13): 110517a (1987) with STN Printout.
Chemical Abstracts Service Registry Handbook Number Section 1965-1971, No. 30525-89-4.

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