Chemistry: molecular biology and microbiology – Apparatus – Including condition or time responsive control means
Patent
1997-09-02
2000-08-01
Housel, James C.
Chemistry: molecular biology and microbiology
Apparatus
Including condition or time responsive control means
435325, 435383, 4352841, 4352871, 4352891, C12M 302
Patent
active
060965320
ABSTRACT:
A processor apparatus is disclosed, for conditioning a portable cassette as part of a process in which biological cells contained within a sterilizable cell growth chamber of the cassette are maintained and grown ex vivo, without exposing the cells to the external environment. The processor apparatus includes a support configured to removably receive the portable cassette and to be movable in a controlled manner, and it further includes a flow control actuator engageable with a media flow path of the portable cassette, which communicates with the cell growth chamber. The processor apparatus further includes a controller that controls the flow control actuator and the support, such that a quantity of growth medium is selectively delivered to the cell growth chamber, such that the cassette is moved in a manner that properly distributes the biological cells throughout the chamber, and such that biological cells are harvested from the cell growth chamber, all without exposing the chamber and the media flow path to the external environment. The processor apparatus also may be configured to retrieve data from, and to store data to, an updatable memory device carried on the portable cassette.
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Armstrong R. Douglas
Maluta James
Roecker David W.
Aastrom Biosciences, Inc.
Brueggemann James R.
Housel James C.
Shaver Jennifer
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