Soft tissue implants for promoting tissue adhesion to same

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis

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623 1, 623 66, 427 2, A61F 202, A61F 206

Patent

active

048713660

ABSTRACT:
A soft tissue implant comprises a flexible main body portion, having tissue-facing surfaces and a thin layer of pure titanium covering the tissue-facing surfaces. A method of promoting tissue adhesion of a soft tissue host to the tissue-facing surfaces of a soft tissue implant comprising a strip of polyethylene terephthalate velour comprises the steps of cleaning the strip with a low-residue detergent and rinsing same with fresh distilled water; refluxing the strip in distilled water for one hour at a temperature of less than 30.degree. C.; drying the strip in a room-temperature desicator for several days; sterilizing the strip and packaging same; degasing the strip and storing same in a dust-free environment; removing the strip from the packaging and mounting the strip in the vacuum evaporator at an approximate angle of incidence of 90.degree. from a pure titanium metal evaporant; evacuating the vacuum evaporator to a vacuum of about 2.times.10.sup.-5 Torr; evaporating the titanium by direct resistance heating same; coating the strip with a layer of pure titanium on the order of one micron thick; and resterilizing and implanting the titanium-coated strip into the tissue host.

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Kasemo, B. Ph.D "Biocopatibility of Titanium Implants: Surface Science Aspects," Journal of Prosthetic Dentistry, 49: 832-837, 1983.
Lundgren et al., "Morphometric Analysis of Tissue Component Adjacent to Percutaneous Implants," pp. 173-181 of Tissue Integration in Oral and Maxillo-Facial Reconstruction, Proceedings of an International Congress held May 1985, Brussels, published around Mar. 18, 1986 by Excerpta Medica, D. van Steenberghe, Editor.
Abstract of Lundgren et al., "Morphometric Analysis of Tissue Components Adjacent to Percutaneous Implants," published @ p. 14 of Abstract Book of the International Congress on Tissue Integration in Oral and Maxillo-Facial Reconstruction, Brussels Convention Hall, published May 22, 1985.
P.C.T. International Publication No. WO 86 02824 entitled, "Element for Controlled Growth into Surgically Intervened Areas," published May 22, 1986, Inventor Lundgren.
von Recum, "Basic Healing Phenomena Around Permanent Percutaneous Implants," published @ pp. 159-172 in Tissue Integration in Oral and Maxillo-Facial Reconstruction, Proceedings of an International Congress held May 1985, Brussels, published around Mar. 18, 1986 by Excerpta Medica, D. van Steenberghe, Editor.

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