Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase
Patent
1994-03-30
1998-02-03
Tsang, Cecilia J.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving hydrolase
435 4, 435 29, 435805, 435810, 436 63, 422 56, 422 58, 422 61, 422102, 128760, 128762, 128769, 128771, C12Q 140, G01N 2100, A61B 500
Patent
active
057143412
ABSTRACT:
An improved method for determining the presence of an analyte in an oral fluid sample. A portion of the sample is mixed or contacted with a chromogenic substrate effective to produce a colored product upon reaction with .alpha.-amylase present in the sample. After a selected reaction time, the reaction mixture is inspected to determine the level of such colored product produced. Production of a level of colored product above a selected threshold within the reaction time indicates that an effective volume of undiluted oral fluid sample has been collected which is sufficient to allow detection of the analyte. A device for use in the method is also disclosed.
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Cimler B. Melina
Klimkow Nanette M.
Thieme Thomas R.
Epitope, Inc.
Mohamed Abdel A.
Tsang Cecilia J.
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