Compositions – Organic luminescent material containing compositions – Scintillating or lasing compositions
Patent
1995-06-07
1998-02-03
McKane, Joseph
Compositions
Organic luminescent material containing compositions
Scintillating or lasing compositions
25230116, 25230134, 25230135, 436536, 436800, 436806, 546 2, 546 8, C09G 1106, C07F 1500
Patent
active
057140898
ABSTRACT:
A chemical moiety is disclosed which comprises a chemical, biochemical, or biological substance attached to one or more electrochemiluminescent organometallic compounds. In a preferred embodiment of the invention the substance is attached to one or more ruthenium-containing or osmium-containing luminescent organometallic compounds. Methods are disclosed for detecting low concentrations of the chemical moiety using chemiluminescent, electrochemiluminescent, and photoluminescent means. Compounds are disclosed which are useful for labeling substances of interest with ruthenium-containing and osmium-containing labels or other electrochemiluminescent labels. These labeled substances are useful in methods provided for detecting and quantifying analytes of interest in binding assays and competitive binding assays. The labeled substances are of particular use in homogeneous binding assays. These methods form the bases for systems designed to enable the rapid, efficient, and sensitive determination of a broad array of chemical, biochemical, and biological materials of interest.
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Bard Allen J.
Whitesides George M.
Evans, Esq. Barry
IGEN International Inc.
McKane Joseph
Rubin, Esq. David
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