PGD.sub.2 Substituted esters

Details PGD.sub.2 Substituted esters PGD.sub.2 Substituted esters

Filed on

1975-10-23

Date issued

1977-05-31

Examiner

Gerstl, Robert

Patent Class

Chemistry of carbon compounds

SubClass

Miscellaneous organic carbon compounds

SubSubClass

C-metal

Other Related Categories

C07C17700

Type

Patent

Status

active

Patent number

040269191

Description

ABSTRACT:
The p-benzamidophenyl, p-(p'-acetamidobenzamido)phenyl, p-acetylphenyl, n-decyl, p-bromophenacyl, and .alpha.-semicarbazono-p-tolyl esters of PGD.sub.2 are disclosed with the process for their preparation. These compounds are useful for the same pharmacological purposes as PGD.sub.2, particularly and especially as platelet aggregation inhibitors.

REFERENCES:
patent: 3767813 (1973-10-01), Samuelsson
patent: 3816393 (1974-06-01), Hayashi et al.
Fiesen et al., Reagents For Organic Synthesis, 1, pp. 86, 1229 (1967).

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