Substituted benzopyrano [3,4-c]pyridines for the treatment of br

Details Substituted benzopyrano [3,4-c]pyridines for the treatment of br Substituted benzopyrano [3,4-c]pyridines for the treatment of br

1975-10-15

1976-10-05

Drezin, Norman A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424246, 424250, 424263, 424267, A61K 3154, A61K 31535, A61K 3144, A61K 31445

Patent

active

039845460

ABSTRACT:
Substituted benzopyrano[3,4-c]pyridines having the following structural formula are disclosed: ##SPC1##
In the above formula, R.sub.1 and R.sub.2 are hydrogen, a hydroxyl group or a lower alkoxyl group of from 1 to 6 carbon atoms; and X is an oxygen atom, a sulfur atom, a methylene group or a nitrogen atom substituted by hydrogen, a lower alkyl group of from 1 to 6 carbon atoms or a lower alkanoyl group of from 1 to 6 carbon atoms. The compounds of this invention are prepared by reacting an R.sub.1, R.sub.2 -substituted phenol with a 3-carbethoxy-4-piperidone in the presence of an acid catalyst to give an intermediate R.sub.1, R.sub.2 -substituted benzopyrano[3,4-c]pyridine. N-aminoalkylbenzopyrano[3,4-c]pyridines are obtained by treating the benzopyrano[3,4-c]pyridine with an appropriately substituted alkyl halide. The compounds of this invention are useful as bronchodilators for the treatment of bronchial asthma.

REFERENCES:
patent: 3396165 (1968-08-01), Bolger
patent: 3429889 (1969-02-01), Shulgin
patent: 3514464 (1970-05-01), Pars
Sakurai, Akio, et al., Bull. Chem. Soc., Japan, 1971, 44 (6), 1677-1682.

Affiliated with

Also associated with

Rating

Substituted benzopyrano [3,4-c]pyridines for the treatment of br does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted benzopyrano [3,4-c]pyridines for the treatment of br, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted benzopyrano [3,4-c]pyridines for the treatment of br will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-655739