Process for the production of 2-bromo-3-cyano-4,6-diaminopyridin

Details Process for the production of 2-bromo-3-cyano-4,6-diaminopyridin Process for the production of 2-bromo-3-cyano-4,6-diaminopyridin

1978-03-06

1980-02-19

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21357

Patent

active

041895843

ABSTRACT:
A process for the production of 2-bromo-3-cyano-4,6-diaminopyridine by cyclization of malodinitrile with hydrogen bromide, which comprises reacting malodinitrile in lower aliphatic hydrogenated hydrocarbons with hydrogen bromide used in an excess of 1 to 10% above the stoichiometric amount at temperatures of -10.degree. C. to +30.degree. C.

REFERENCES:
patent: 2790806 (1957-04-01), Middleton
Middleton, Chem. Abstracts, vol. 51, (19) p. 14,828f-g, Oct. 10, 1957.

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