Compositions and methods for generating red chemiluminescence

Details Compositions and methods for generating red chemiluminescence Compositions and methods for generating red chemiluminescence

1998-12-09

1999-10-12

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548113, C07F 708, C07F 96539

Patent

active

059657367

ABSTRACT:
Compounds which generate red chemiluminescence on reaction with a phosphatase enzyme are provided as well as intermediates useful for their preparation. The chemiluminescent compounds comprise a luciferin ring system and an exocyclic enol phosphate group where the position on the luciferin ring system adjacent to the double bond is disubstituted. The chemiluminescent compounds are useful alone or within compositions containing a cationic aromatic compound in methods for producing chemiluminescence. The chemiluminescent reactions can be applied in assays for phosphatase enzymes and in assays employing enzyme-labeled specific binding pairs.

REFERENCES:
patent: 5629168 (1997-05-01), Kricka
T.A.Hopkins H.H.Seliger E.H.White M.W.Cass, J.Am.Chem.Soc., 89, 7148-7150 (1967).
W.D.McElroy H.H.Seliger E.H.White, Photochem. Photobiol., 10, 153-170 (1969).
E.H.White H.Worther, J.Org.Chem., 31, 1484-1488 (1966).
E.H.White H.Worther H.H.Seliger W.D.McElroy, J.Am.Chem.Soc., 88, 2015-2019 (1966).

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