5-Fluorouracil derivatives

Details 5-Fluorouracil derivatives 5-Fluorouracil derivatives

1980-11-03

1982-06-22

Coughlan, Jr., Paul M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D23955

Patent

active

043363814

ABSTRACT:
Orally administrable 5-fluorouracil derivatives of the general formula: ##STR1## [wherein R.sup.1 is aryl or substituted aryl; R.sup.2 is acyclic or cyclic alkyl, adamantyl, aryl or substituted aryl; R.sup.3 and R.sup.4 are the same or different, each representing hydrogen atom or lower alkyl] effective against malignant tumors.

REFERENCES:
patent: 4124765 (1978-11-01), Kurono et al.
patent: 4267326 (1981-05-01), Ozaki et al.

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