Class two cytokine receptor-11

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

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530300, 530351, 536 231, 536 235, C07K 14715

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active

059657049

ABSTRACT:
Novel class II cytokine receptor polypeptides, polynucleotides encoding the polypeptides, an related compositions and methods are disclosed. Th polypeptides comprise an extracellular domain of a cell-surface receptor that is expressed in pancreas, small intestine, colon and thymus. The polypeptides may be used within methods for detecting ligands that promote the proliferation and/or differentiation of these organs.

REFERENCES:
patent: 5789192 (1998-08-01), Moore et al.
Liu et al., Journal of Immunology 152:1821-1829, 1994.
Hillier et al., The Wash U-Merck EST Project, Feb. 23, 1995, GenBank Acc. No.:T70354.
Hillier et al., The Wash U-Merck EST Project, Feb. 23, 1995, GenBank Acc. No.:T70439.
Hillier et al., GenBank Accession No.:AA132964, Nov. 27, 1996.
Hillier et al., GenBank Accession No.:T70439, Feb. 23, 1995.
Henikoff et al., Amino acid substitution matrices from protein blocks, Proc. Natl. Acad. Sci., USA, 89:10915-10919, Nov. 1992.
Stites et al., eds., Basic and Clinical Immunology, Appleton & Lange: Norwalk, CT, p. 53, 1994.

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