Somatostatin mimics and synthetic methods therefor

Details Somatostatin mimics and synthetic methods therefor Somatostatin mimics and synthetic methods therefor

1994-11-16

1999-10-12

Russel, Jeffrey E.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Somatostatin ; related peptides

514 11, 930160, A61K 3831, C07K 14655

Patent

active

059656948

ABSTRACT:
Relatively small cyclic peptides that mimic the biological and/or chemical activity of larger cyclic peptide such as somatostatin, as well as synthetic methods therefor. In certain embodiments, cyclic peptides of the invention have structure: ##STR1## wherein R.sub.NP1 is H, an amine protecting group, or a solid support and R.sub.NP2 is H or an amine protecting group.

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