Treatment of scar tissue using lipoic acid

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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514440, A61K 3120, A61K 31385

Patent

active

059656182

ABSTRACT:
Scar tissue is reduced or inhibited by application of a composition containing lipoic acid and/or a lipoic acid derivative such as dihydrolipoic acid, a lipoic or dihydrolipoic acid ester, a lipoic or dihydrolipoic acid amide, a lipoic or dihydrolipoic acid salt, and mixtures of any of these. Some compositions further comprise .alpha.-hydroxy acids or acid derivatives such as glycolic and/or lactic acid, fatty acid esters of ascorbic acid such as ascorbyl palmitate, and/or tocotrienol. In some embodiments, a silicone gel sheet with added lipoic acid and/or a lipoic acid derivative and optional other ingredients is topically applied to scar tissue to diminish them.

REFERENCES:
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patent: 5472698 (1995-12-01), Rawlings et al.
patent: 5569670 (1996-10-01), Weisher et al.
patent: 5693664 (1997-12-01), Wessel et al.
patent: 5728735 (1998-03-01), Ulrich et al.
Yu et al. 126;CA 1354475.

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