Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1994-04-04
1995-04-18
Mars, Howard T.
Drug, bio-affecting and body treating compositions
Dentifrices
514171, A61K 728, A01N 4500
Patent
active
054076633
ABSTRACT:
Patients may effectively be treated for inflammatory conditions of the mouth using aqueous anti-inflammatory steroids in solutions that can be swished and expectorated as a mouthwash. Such therapy would allow direct contact of the medication with the diseased mucous membranes and would contact areas of the oral cavity that would not usually be reached with application of creams, gels, or ointments. Compositions containing antifungal agents in addition to steroids are particularly useful.
Swishing for three to five minutes, then expectorating the aqueous anti-inflammatory-containing, results in maintenance of contact of the active agents with the oral cavity surfaces for a longer time than would application of gels containing those agents. The mode of application is simple and is not repugnant to the patient as is the application of creams, gels, or ointments.
REFERENCES:
Rothwell et al, Special Care in Dentistry, 1990, pp. 21-25.
Facts and Comparisons, Adrenal Cortical Steroids, 1984, pp. 119-128b.
Vademecum Internacional Especiales Farmaceuticas y Biologicas. (1984) Barcelona, pp. 490-587.
Cook Rebecca
Gates Stephen
Hendricks Glenna
Mars Howard T.
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