Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1994-02-28
1995-04-18
Acquah, Samuel A.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
528272, 528274, 528275, 528277, 528278, 528280, 528289, 528290, 528293, 528295, 528296, 528298, 528299, 528300, 528302, 528307, 528308, 528332, 528335, 528342, 528350, 528354, 525437, 525443, 525444, 1286532, 1286534, 436173, 436806, 600 12, A61K 4900, A61B 600, C08F 2000
Patent
active
054076579
ABSTRACT:
Novel MRI contrast agents that comprise one or more metal-ion chelates in juxtaposition with one or more free-radical nitroxide compounds in a polymeric or oligomeric molecule. Both the chelate units and the free radical units may, independently, be inside the main chain of the polymer or in a side chain of the linkage portion of the polymer. The number of combined units of chelates and free radicals in the polymer or oligomer is at least two.
REFERENCES:
patent: 4822594 (1989-04-01), Gibby
patent: 4834964 (1989-05-01), Rosen
patent: 4863717 (1989-09-01), Keana
patent: 4933441 (1990-06-01), Gibby
patent: 5104641 (1992-04-01), Rosen
patent: 5135737 (1992-08-01), Keana
Unger Evan C.
Wu GuanLi
Acquah Samuel A.
Durando Antonio R.
Weiss Harry M.
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