Hybrid magnetic resonance contrast agents

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent

Patent

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528272, 528274, 528275, 528277, 528278, 528280, 528289, 528290, 528293, 528295, 528296, 528298, 528299, 528300, 528302, 528307, 528308, 528332, 528335, 528342, 528350, 528354, 525437, 525443, 525444, 1286532, 1286534, 436173, 436806, 600 12, A61K 4900, A61B 600, C08F 2000

Patent

active

054076579

ABSTRACT:
Novel MRI contrast agents that comprise one or more metal-ion chelates in juxtaposition with one or more free-radical nitroxide compounds in a polymeric or oligomeric molecule. Both the chelate units and the free radical units may, independently, be inside the main chain of the polymer or in a side chain of the linkage portion of the polymer. The number of combined units of chelates and free radicals in the polymer or oligomer is at least two.

REFERENCES:
patent: 4822594 (1989-04-01), Gibby
patent: 4834964 (1989-05-01), Rosen
patent: 4863717 (1989-09-01), Keana
patent: 4933441 (1990-06-01), Gibby
patent: 5104641 (1992-04-01), Rosen
patent: 5135737 (1992-08-01), Keana

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