Thienothiazine derivatives

Details Thienothiazine derivatives Thienothiazine derivatives

1978-10-30

1980-09-23

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544327, 544331, 544405, 546284, 548128, 548195, 548245, 548246, 549 64, C07D33338, C07D33340

Patent

active

042244455

ABSTRACT:
The present invention relates to compounds of the formula ##STR1## wherein A together with the two carbon atoms to which it is attached forms the group ##STR2## and the broken line represents the double bond in group (a); R.sub.1 represents a lower alkyl group; R.sub.2 represents the residue of an aromatic heterocyclic ring containing from 1 to 4 hetero atoms, which may be substituted by one or two lower alkyl groups, or a phenyl group which may be substituted by halogen, hydroxy, lower alkyl, trifluoromethyl or lower alkoxy and R.sub.3 and R.sub.4 each represent a hydrogen atom or a lower alkyl group.
Also provided are methods for their preparation. The thienothiazine derivatives provided by this invention have anti-flammatory, analgesic and anti-rheumatic activity.

REFERENCES:
patent: 4076709 (1978-02-01), Hromatka

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