Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1984-10-10
1986-10-07
Hendricks, Glenna M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548452, A61K 3140, C07D20942
Patent
active
046160310
ABSTRACT:
Compounds of the general formula: ##STR1## wherein: the ring A is saturated and n=0 or 1, or
REFERENCES:
patent: 3501497 (1970-03-01), Bell
patent: 3514465 (1970-05-01), Posselt et al.
patent: 4046889 (1977-09-01), Ondetti et al.
patent: 4105776 (1978-08-01), Ondetti et al.
patent: 4251444 (1981-02-01), Freed et al.
patent: 4256751 (1981-05-01), Hayashi et al.
patent: 4303583 (1981-12-01), Kim et al.
patent: 4344949 (1982-08-01), Hoefle et al.
patent: 4350633 (1982-09-01), Kim et al.
patent: 4374829 (1983-02-01), Harris et al.
patent: 4404206 (1983-09-01), Vincent et al.
Burger, Alfred; Medicinal Chem., vol. I, pp. 75, 76, (1970).
Wollweber et al., "Compounds Active on Blood Pressure", Chem. Abst. 57: 16561 (f), (1962).
Wagner and Zook; Synthetic Organic Chemistry, pp. 662, 663, (1953).
Vincent et al., "Stereoselective Synthesis . . . Perhydroindole . . . ", Tetrahedron Letters, vol. 23, pp. 1677-1680, (1982).
Patchett et al., ". . . Angiotensin-Converting Enzyme Inhibitors", Nature, vol. 288, pp. 280-283, (1980).
The Merck Index, 9th Edition (1976), pp. 656, 657, items 4840-4852.
Burger, Alfred; "Medicinal Chemistry", 3rd Edition, Part II, relating to Antihypertensive Agents , pp. 1019-1055.
Burger, Alfred; "Medicinal Chemistry", 4th Edition, Part III, relating to Antihypertensive Agents , pp. 324, 325.
Scriabine; "Pharmacology of Antihypertensive Drugs", relating to Guanethidine, pp. 127, 196, 211; and Alprenolol, p. 223; and Pindolol, p. 237; and, relating to Other Beta-Adrenoceptor Antagonists, pp. 350, 351.
Gross et al.; Journal of Pharmacology and Experimental Therapeutics", 1981, 216, (3), pp. 552-557.
Laubie Michel
Remond Georges
Vincent Michel
ADIR
Hendricks Glenna M.
Hueschen Gordon W.
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