Antifungal 2-aryl-1,1-difluoro-3-(1H-1,2,4-triazol-1-yl)2-propan

Details Antifungal 2-aryl-1,1-difluoro-3-(1H-1,2,4-triazol-1-yl)2-propan Antifungal 2-aryl-1,1-difluoro-3-(1H-1,2,4-triazol-1-yl)2-propan

1983-07-25

1986-10-07

Rollins, Alton D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

260665R, 260665G, 514383, 546268, 546276, 548252, 548262, 549563, 556415, 562496, A01N 43653, A01N 43713, C07D24908, C07D40306

Patent

active

046160264

ABSTRACT:
Compounds of the formula ##STR1## a pharmaceutically or agriculturally acceptable acid addition salt thereof wherein R is 5-chloro-2-pyridyl, phenyl or phenyl substituted by from 1 to 3 substituents, each independently selected from F, Cl, Br, I, CF.sub.3, (C.sub.1 -C.sub.4)alkyl and (C.sub.1 -C.sub.4)alkoxy; and R.sup.1 is H, Cl, phenyl, phenyl substituted by from 1 to 3 substituents each independently selected from F, Cl, Br, I and CF.sub.3 or a heterocyclic group linked to the adjacent CF.sub.2 group by a ring carbon atom; method for their use in combatting fungal infections in plants, seeds and animals, including humans, and pharmaceutical and agricultural compositions containing them.

REFERENCES:
patent: 4243405 (1981-01-01), Balasubramanyan et al.
patent: 4386088 (1983-05-01), Knanz et al.
patent: 4483863 (1984-11-01), Richardson et al.
Burger, Medicinal Chemistry, (Second Edition, New York, 1960), p. 1055, RS 403B8.

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