Novel diacylglycerophosphoric acid esters and use thereof as sub

Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus esters

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

549216, 549220, 260403, 435 21, C07F 902, C07F 910, C12Q 142

Patent

active

050119648

ABSTRACT:
Novel diacylglycerophosphoric acid esters include a hydrophobic diacyl glycerol portion to provide water insolubility and a head group which forms a chromophore or a chromophore precursor when the head group is enzymatically released and are chromogenic substrates useful to assay for enzymes catalyzing the cleavage of phosphate ester or phosphoanhydride bonds adjacent or opposite to the phosphatidic acid region of a phospholipid molecule.

REFERENCES:
patent: Re30748 (1981-09-01), Sears
patent: 3875013 (1975-04-01), Manauton et al.
patent: 3960905 (1976-06-01), Eibl et al.
patent: 4039388 (1977-08-01), Gal et al.
patent: 4041111 (1977-08-01), Kelly et al.
patent: 4102747 (1978-07-01), Driscoll
patent: 4129650 (1978-12-01), Betzing et al.
patent: 4145527 (1979-03-01), Burns
patent: 4147860 (1979-04-01), Farnham
patent: 4225672 (1980-09-01), Hall
patent: 4233403 (1980-11-01), Menson et al.
patent: 4263286 (1981-04-01), Nakajima et al.
patent: 4316730 (1982-02-01), Eibl
patent: 4348329 (1982-09-01), Chapman
patent: 4426330 (1984-01-01), Sears
patent: 4451563 (1984-04-01), Kaufman
patent: 4472499 (1984-09-01), McCroskey
Carman et al., Analytical Biochemistry 110, 73-76 (1981).
Dawson et al., Biochemistry Journal, 102, 76-86 (1967).
Imamura et al., Journal of Biochemistry, 83, 677-680 (1978).
Mynarcik et al., Federation Proceedings, Abstracts ASBC/AAI Annual Meeting, American Societies for Experimental Biology, vol. 43, No. 6, 1458, Abstract #243 (5/1/84).
Van Boeckel, C. A. A. et al., Tetrahedron, 37(21), 3751-3761 (1981).
Dixon, M. et al., Enzymes, Academic Press, pp. 199-204 (1964).
Stenish, J. Dictionary of Biochemistry, John Wiley & Sons, p. 237 (1975).
Stryer, L. Biochemistry, 2d Edition, W. H. Freeman and Co., p. 461 (1981).
Bahl, O. P., The Journal of Biological Chemistry, 245, No. 2, Issue of Jan. 25, 1970, pp. 299-304.
Aminoff, D. et al., The Journal of Biological Chemistry, 245, No. 7, Issue of Apr. 10, 1970, pp. 1659-1669.
Yurewicz, E. C. et al., The Journal of Biological Chemistry, 246, No. 18, Issue of Sep. 25, 1971, pp. 5607-5616.
Kozak, E. M. et al., The Journal of Biological Chemistry, 257, No. 11, Issue of Jun. 10, 1982, pp. 6322-6327.
Barman, T. E. Enzyme Handbook, vol. 1, pp. 521-524, 544, 545, 560-561, 576-579, Springer-Verlang, New York, Inc. 1969.
Hofmann, S. L. et al., The Journal of Biological Chemistry (1982), vol. 257, pp. 6461-6469.
Jencks, W. P., Catalysis in Chemistry and Enzymology, McGraw-Hill, 1969, pp. 60-65.
Yang, S. F. et al., The Journal of Biological Chemistry, (1967), vol. 242, pp. 477-484.
de Lumen, B. O. et al., The Journal of Biological Chemistry, 247, No. 11, Issue of Jun. 10, 1972, pp. 3552-3557.
Saito, M. et al., Archives of Biochemistry and Biophysics, 164, 420-428 (1974).
Enzyme Nomenclature, Academic Press, pp. 248, 250 (1978).
Calama, M. A. et al., Chemical Abstracts, 75: 1983 y (1971).
Boehringer Catalog, pp. 461 and 463.
Billah, M. M. et al., Journal of Biological Chemistry, 264 (69) 17069-17077 (1989).
Davitz, M. A., Science, 238, pp. 81-84 (10/87).
Kurioka, S. et al., Analytical Biochemistry 75, 281-289 (1976).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Novel diacylglycerophosphoric acid esters and use thereof as sub does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel diacylglycerophosphoric acid esters and use thereof as sub, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel diacylglycerophosphoric acid esters and use thereof as sub will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-641466

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.