Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1990-04-30
1991-04-30
Weimar, Elizabeth C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D31182
Patent
active
050119524
ABSTRACT:
A compound of the formula: ##STR1## wherein the wave line means .alpha.-bond or .beta.-bond, which compound is useful as a phospholipase A.sub.2 inhibitor. Process for the production of the compound, pharmaceutical composition containing the compound, and a cell culture of a microorganism Thielavia terricola RF-143 producing the compound are also provided.
REFERENCES:
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Kolly et al., Chemical Abstracts, vol. 110, No. 13, 27 Mar. 1989, p. 672, Abstract No. 114635f.
Endo et al., Chemical Abstracts, vol. 91, No. 25, 17 Dec. 1979, p. 519, Abstract No. 209363u.
Kitahara et al., Chemical Abstract, vol. 96, No. 7, 15 Feb. 1982, p. 295, Abstract No. 48698t.
Kitahara et al., Chemical Abstracts, vol. 99, No. 5, 1 Aug. 1983, p. 506, Abstract No. 38273y.
Emmono, Bulletin of the Torrey Biotanical Club, vol. 57, No. 2, Feb. 1930, pp. 123-126.
Arita Hitoshi
Inoue Keizo
Kawamura Yoshimi
Matsutani Shigeru
Shoji Jun'ichi
Shionogi & Co. Ltd.
Webber Pamela S.
Weimar Elizabeth C.
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