Prognostic markers in human breast cancer

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 79, 435 792, 435 794, 436 63, 436 64, 436813, 424 149, G01N 33574, G01N 3353, G01N 33543

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active

054159962

ABSTRACT:
Methods and compositions are provided for determining the prognosis of human breast carcinoma through in vitro or in vivo detection of an antigen expressed and shed by cancer cells. The presence of this antigen is positively correlated with the presence of cancer and the number of cells expressing this antigen is correlated with a high incidence of tumor relapse, distant relapse and shortened relapse-free survival time.

REFERENCES:
patent: 5019497 (1991-05-01), Olsson
Martensson, S., et al., Cancer Res, vol. 48(8), pp. 2125-2131, Apr. 15, 1988.

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