Nonapeptide and decapeptide analogs of LHRH, useful as LHRH agon

Details Nonapeptide and decapeptide analogs of LHRH, useful as LHRH agon Nonapeptide and decapeptide analogs of LHRH, useful as LHRH agon

1983-11-07

1985-07-23

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514800, 2601125R, C07C10352, A61K 3702

Patent

active

045309205

ABSTRACT:
Synthetic nonapeptide and decapeptide LHRH agonists analogs having a novel gaunadino-substituted, amidine, tertiary or quatrinary aminoacyl residue at position 6 are disclosed herein.

REFERENCES:
patent: 3773919 (1973-11-01), Boswell et al.
patent: 3972859 (1976-08-01), Fujino et al.
patent: 4010125 (1977-03-01), Schally et al.
patent: 4215038 (1980-07-01), Rivier et al.
patent: 4341767 (1982-07-01), Nestor et al.
Beattie, J. Am. Med. Chem., 18 (No. 12), 1247-1250 (1975).
Horvath et al., Peptides, 3, 969-971 (1982) printed in U.S.A.
Chemical Abstracts, 88, 631 (1978), Abst. No. 7331j.
Coy et al., Endocrinology, 110 (No. 4), 1445-1447 (1982).

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