Prolonged release of biologically active polypeptides

Details Prolonged release of biologically active polypeptides Prolonged release of biologically active polypeptides

1995-12-11

1998-04-14

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530399, A61K 3827, C07K 1461

Patent

active

057391084

ABSTRACT:
Prolonged parenteral release of a bioactive polypeptide at desirably effective levels can be achieved using novel compositions in which the polypeptide is present in a biocompatible oil in an unusually high proportion such as at least about 10% by weight. Also disclosed are certain metal-associated somatotropins that are useful for prolonged parenteral release of such somatotropins.

REFERENCES:
patent: 3869549 (1975-03-01), Geller
patent: 4659696 (1987-04-01), Hirai et al.
patent: 5013713 (1991-05-01), Mitchell
patent: 5086041 (1992-02-01), Mitchell
patent: 5411951 (1995-05-01), Mitchell
patent: 5474980 (1995-12-01), Mitchell
Davis et al. "Continuous Elevation of Blood Growth Hormone Concentrations by Beeswax Implant", J. Dairy Science 66: 1980-1982.

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