Substituted amino alkyl pyridyl ethanediimidamides

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546300, 546255, 546261, 546270, 546281, 546194, 544124, 544 60, 544360, 2602444, C07D40106

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active

045784710

ABSTRACT:
Histamine H.sub.2 -receptor antagonists of the formula ##STR1## wherein A, m, Z, n and R.sup.1 are as defined herein, and their nontoxic pharmaceutically acceptable salts, hydrates and solvates are novel anti-ulcer agents which are prepared by ring closure of a substitutted ethanediimidamide of the formula ##STR2##

REFERENCES:
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patent: 4374248 (1983-02-01), Crenshaw et al.
patent: 4440933 (1984-04-01), Montzka
Komin et al., J. Het. Chem., 13, 13-22, (1976).
Komin et al., J. Org. Chem., 40, 2749-2752, 1975.
Weinstock et al., J. Org. Chem., 32, 2823-9, 1967.
Katritsky et al., Advances in Heterocyclic Chem., vol. 9, 1978, 107-163.

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