Nitrile compounds useful as intermediates in the production of b

Details Nitrile compounds useful as intermediates in the production of b Nitrile compounds useful as intermediates in the production of b

1995-03-09

1996-04-30

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20948

Patent

active

055126820

ABSTRACT:
Nitriles of formula ##STR1## wherein R3 is acetoxy or benzyloxycarbonyl, useful as intermediates in the production of beta-aminoalcohols.

REFERENCES:
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patent: 4462943 (1984-07-01), Petrillo, Jr. et al.
patent: 5157041 (1992-10-01), Handa et al.
patent: 5236783 (1993-10-01), Gokhale et al.
Melon, et al, Enantiomerically pure 3-amino-2-hydroxy and 5-amino-4-hydroxy acids from D-isoascorbic acid, Bull Soc. Chim Fr, vol. 129, pp. 585-593 (1992).
Iizuka, et al, Orally Potent Human Renin Inhibitors Derived from Angiotensinogen Transition State: Design, Synthesis, and Mode of Interaction, J. Med. Chem. vol. 33, pp. 2707-2714 (1990).

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