Pharmaceutical composition of botulinum neurotoxin and method of

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 2, 530350, 530363, 530364, 530825, A61K 3800, C07K 100

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active

055125476

ABSTRACT:
Pharmaceutical compositions of botulinum neurotoxin containing higher specific toxicity and increased stability at higher temperatures than currently available preparations.

REFERENCES:
Goodnough et al, Applied and Environmental Microbiology, vol. 58, No. 10, pp. 3426-3428, Oct. 1992.
Schantz, E. J. and Scott, A. B., Biomedical Aspects of Botulism, Academic Press, Inc., pp.143-150 (1981).
Schantz, E. J., and Kautter, D. A., Journal of the Association of Official Analytical Chemists, vol. 61, pp. 96-99 (1978).
Melling et al., "Clostridium Botulinum Toxins: Nature and Preparation for Clinical Use." Eye, vol. 2, 1988, pp.-16-23.
Hambleton et al. "Production, Purification and Toxoiding of Clostridium Botulinum Type A Toxin", Biomedical Aspects of Botulism, Academic Press, Inc., (1981) pp. 247-260.

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