Thieno[3,2-b]pyridine-6-carboxamide compounds useful in treating

Details Thieno[3,2-b]pyridine-6-carboxamide compounds useful in treating Thieno[3,2-b]pyridine-6-carboxamide compounds useful in treating

1987-11-19

1989-10-31

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546114, C07D21332

Patent

active

048777935

ABSTRACT:
Novel 7(4H)-thieno[3,2-b]pyridinones of the formula I, ##STR1## wherein R is lower alkyl, and R.sub.1 is hydrogen, lower alkyl, lower alkoxy, halo, trifluoromethyl, or phenyl optionally substituted with one or two substituents selected from halo, lower alkyl, lower alkoxy and trifluoromethyl.
The compounds are useful in the treatment of cardiovascular diseases. Pharmaceutical compositions containing the novel compounds and processes for preparing the novel compounds are also described.

REFERENCES:
patent: 3903095 (1975-09-01), Shen et al.
patent: 3997545 (1976-12-01), Kuwada et al.
patent: 4302460 (1981-11-01), Davies et al.
patent: 4442109 (1984-04-01), Davies
patent: 4447435 (1984-05-01), Davies
patent: 4552884 (1985-11-01), Sim et al.
patent: 4659718 (1987-04-01), Davies et al.
patent: 4710506 (1987-12-01), Davies et al.

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