Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1988-03-02
1989-10-31
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
436507, 436519, 436811, 530350, 530403, 530822, G01N 33569, C07K 1504
Patent
active
048777269
ABSTRACT:
A method of detecting Toxoplasma infection and distinguishing acute infection from chronic infection is provided, comprising the steps of combining a sample suspected of containing antibodies to Toxoplasma antigens with a acute-phase-specific antigen reactive with an antibody specific for an acetone-treated Toxoplasma antigen under conditions favorable for formation of antigen-antibody complex, and detecting formation of the complex.
REFERENCES:
patent: 4361647 (1982-11-01), Remington
patent: 4480043 (1984-10-01), Trouyez
patent: 4609630 (1986-09-01), Yanovsky
Infect. Immun., 41(2), 683-90, 1983, Erlich, H. et al., Identification of an Antigen-Specific Immunoglobulin M Antibody Associated with Acidic Toxoplasma Infection.
A Practical Manual of Medical & Biological Staining Techniques by Gurr, pp. 3-11, 1956, Interscience Publishers, Inc., N.Y.
Desmonts Georges
Remington Jack S.
Suzuki Yasuhiro
Thulliez Philippe
Neeley Richard L.
Nucker Christine M.
Research Institute of Palo Alto Medical Foundation
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