Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1988-06-16
1990-05-15
Gray, Bruce D.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
560 36, 562433, 562441, 562455, 562456, 562457, C07C10144
Patent
active
049259580
ABSTRACT:
The invention relates to a process for the preparation of compounds of the formula I ##STR1## in which R.sup.1 denotes (substituted) aryl or (substituted) cyclohexyl and R.sup.2 =alkyl, in which a compound of the formula R.sup.1 --NH.sub.2 is reacted with at least twice the molar amount of glyoxylic acid in the presence of water and the resulting acid is then esterified.
REFERENCES:
patent: 4182624 (1980-01-01), Soeder et al.
Eggensperger et al., Chemical Abstracts, vol. 81, No. 3383k, (1974).
"Synthesis of Strombine, a New Method for Monocarboxymethylation of Primary Amines", Jan Kihlberg, Rolf Bergman and Boerje Wickberg, Acta Chemica Scandinavica B 37 (1983), pp. 911-916.
Kunstmann Rudolf
Schmierer Roland
Gray Bruce D.
Hoechst Aktiengesellschaft
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