Derivative of codeine useful as an agonist and process for the p

Details Derivative of codeine useful as an agonist and process for the p Derivative of codeine useful as an agonist and process for the p

1988-04-28

1990-05-15

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 40, 546 45, A61K 31485, C07D48906

Patent

active

049258486

ABSTRACT:
A compound of the formula: ##STR1## A process for its preparation and pharmaceutical compositions comprising the compound or a pharmaceutically acceptable salt thereof with a pharmaceutically acceptable diluent or carrier. The compound exhibits analgesic activity.

REFERENCES:
patent: 4241066 (1980-12-01), Kobylecki et al.
patent: 4241067 (1980-12-01), Kobylecki et al.
Smith, Life Sciences, vol. 40, No. 3, pp. 267-274 (1987).
de Stevens, ed., "Analygetics", Academic Press, New York (1965), pp. 127, 131.
Allen et al., Chemical Abstracts, vol. 74: 3754n (1971).
Allen, "Synthesis of New Codeinone and Indolinocodeinone Derivatives", Thesis submitted to Loughborough University of Technology, 09/71, cited in Index to These, vol. XXII, 1971-1972, ed., Paterson, et al., Aslib, London (1974), pp. 30-33.

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