Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-06-03
1990-05-15
Sutto, Anton H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514257, 544250, 544281, A61K 31505, C07D48704
Patent
active
049258460
ABSTRACT:
A compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 is thiazol-2-yl optionally substituted by 1 or 2 alkyl of 1 to 3 carbon atoms optionally substituted by one or more fluorine or --COOAlk, Alk is alkyl of 1 to 3 carbon atoms, R.sub.2 and R.sub.3 are individually selected from the group consisting of hydrogen, alkyl of 1 to 3 carbon atoms and alkenyl of 2 to 5 carbon atoms or R.sub.2 and R.sub.3 together form alkylene of 3 to 5 carbon atoms, X is oxygen or sulfur and R.sub.4 is alkyl of 1 to 3 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having minor tranquillizing activity and useful for the treatment of obesity and cognitive impairment.
REFERENCES:
patent: 4521422 (1985-06-01), Dusza et al.
patent: 4703049 (1987-10-01), Gillespie et al.
patent: 4735957 (1988-04-01), Takaya et al.
Deacon Robert M. J.
Gardner Colin R.
Gillespie Roger J.
Tully Wilfred R.
Bernhardt E.
Roussel Uclaf
Sutto Anton H.
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