Antihyperlipidemic and antiatherosclerotic compounds and composi

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

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514539, 514542, 514562, 514563, 514564, 514586, 514587, 514595, 514596, 514598, 514824, 560 10, 560 16, 560 34, 562427, 562428, 562439, 564 26, 564 27, 564 28, 564 29, 564 44, 564 48, 564 52, C07C27528, A61K 31235, A61K 3119, A61K 3117

Patent

active

050306537

ABSTRACT:
Certain N-2,6-dialkyl- or N-2,6-dialkoxyphenyl-N'-arylalkylurea compounds are potent inhibitors of the enzyme acyl CoA:cholesterol acyltransferase (ACAT), and are thus useful agents for the treatment of hypercholesterolemia or atherosclerosis.

REFERENCES:
patent: 3555086 (1971-01-01), Weis et al.
patent: 4868210 (1989-09-01), Trivedi
patent: 4981865 (1991-01-01), Belliotti et al.
Erden, F. et al., "Acyl Enamines, etc.", CA 75, 151493n, 1971.

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