Preparation of substituted 1,2,4-triazolo[1,4-a]pyrimidine-2-sul

Details Preparation of substituted 1,2,4-triazolo[1,4-a]pyrimidine-2-sul Preparation of substituted 1,2,4-triazolo[1,4-a]pyrimidine-2-sul

1989-12-07

1991-03-26

Shaver, Paul F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Silicon containing

C07F 710

Patent

active

050030965

ABSTRACT:
Substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonanilides, which are known herbicides, are prepared by the reaction of substituted 1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonyl halides with substituted N-trialkylsilylanilines in the presence of a base catalyst. The method is especially useful for the preparation of substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonanilides derived from substituted anilines having both 2- and 6-substituents, at least one of which is electron withdrawing, such as N-(2,6-dichlorophenyl)-5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidine-2-sulf onamide. N-trialkylsilylanilines having both 2- and 6-substituents, at least one of which is electron withdrawing, such as N-trimethylsilyl-2,6-dichloro-3-methylaniline, are described.

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