Metal-based antimicrobial coating

Details Metal-based antimicrobial coating Metal-based antimicrobial coating

1988-10-07

1990-06-12

Schofer, Joseph L.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424405, 424422, 424423, 424424, 424617, 424618, 523122, 523112, 523113, 604266, 604265, A61K 3174, A01N 4336, C07C 500, C08J 600

Patent

active

049331787

ABSTRACT:
A medical device with an antimicrobial coating that is safe, effective, photostable and readily manufacturable can be produced by applying a composition to at least one body fluid-contacting surface of the device such that a solid coating is provided on that surface, the coating composition comprising an oligodynamic metal salt of a sulfonylurea, a polymeric material, at least one acid compound selected from the group consisting of a water-soluble carboxylic acid and water-insoluble carboxylic acid, and a carrier liquid in which foregoing components are soluble. The antimicrobial coating accommodates variation in the release of antimicrobial metal ions as a function of the intended use for a medical device to which the coating is applied.

REFERENCES:
patent: 4054139 (1977-10-01), Crossley
patent: 4344431 (1982-08-01), Yolles
patent: 4392848 (1983-07-01), Lucas et al.
patent: 4479795 (1984-10-01), Mustacich et al.
patent: 4581028 (1986-04-01), Fox, Jr. et al.
patent: 4592920 (1986-10-01), Murtfeldt
patent: 4677143 (1987-06-01), Laurin et al.

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