Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1986-02-24
1987-06-02
Brown, Johnnie R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 72, C07H 1708
Patent
active
046705490
ABSTRACT:
A method for the selective methylation of the hydroxy group at the 6-position of erythromycin A derivatives which comprises reacting a compound represented by the formula R-X (wherein R is a 2-alkenyl group, a benzyl group or a substituted benzyl group, and X is a halogen atom), reacting the resulting quaternary salt compound with a methylating agent, and then eliminating R groups of the resulting compound to give 6-O-methylerythromycin A 9-oxime, is disclosed.
REFERENCES:
patent: 3923784 (1975-12-01), Kierstead et al.
patent: 4264765 (1981-04-01), Bodor et al.
patent: 4331803 (1982-05-01), Watanabe et al.
Adachi Takashi
Asaka Toshifumi
Kashimura Masato
Morimoto Shigeo
Sota Kaoru
Brown Johnnie R.
Taisho Pharmaceutical Co. Ltd.
LandOfFree
Method for selective methylation of erythromycin a derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for selective methylation of erythromycin a derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for selective methylation of erythromycin a derivatives will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-614855