Method of controlling graft versus host reaction

Details Method of controlling graft versus host reaction Method of controlling graft versus host reaction

1985-10-30

1987-06-02

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

514574, 514885, A61K 3119

Patent

active

046704671

ABSTRACT:
The present invention discloses a method of controlling graft versus host disease, resulting from bone marrow transplantation by treating the host with succinylacetone. A dosage of about 800 mg/kg body weight every 4 days is found optimal.

REFERENCES:
Chemical Abstracts 98:191394n (1983).
Tschudy et al., J. Lab. and Clin. Med. 99:526-632 (1982).
Tschudy et al., Oncology 40:148-154 (1983).
Pendarvis et al., J. Org. Chem. 39:2289-2291 (1974).
Ebert et al., Biochemical and Biophysical Research Communications 88:1382-1390 (1979).

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