Humectant compositions containing thiamorpholinone or a derivati

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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A61K 3154

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active

045393206

ABSTRACT:
A composition for topical application to the skin comprises, in an appropriate cosmetic vehicle, as an active agent, a compound of the formula ##STR1## wherein, R.sub.1 and R.sub.2 represent hydrogen or lower alkyl; R.sub.3 represents hydrogen, alkyl containing 1-4 carbon atoms, mono- or polyhydroxyalkyl having 2-16 carbon atoms, carbamylalkyl, carboxyalkyl or alkoxycarbonylalkyl; R.sub.4 represents hydrogen or --COOR.sub.5 represents hydrogen, alkyl having 1-18 carbon atoms optionally interrupted by one or more hetero atoms, or mono- or polyhydroxyalkyl having 2-18 carbon atoms; and n is 0 or 1.
This composition improves the elasticity and suppleness of the skin.

REFERENCES:
patent: 2755278 (1956-07-01), Goldberg et al.
Lehr et al., J. Med. Chem., vol. 6, No. 2, pp. 136-141, Mar. 1983.
Chem. Abstracts 84:105613q (1976).
Chem. Abs. 80:146182j (1974).
Bushey et al., J. Org. Chem., vol. 45, No. 21, pp. 4198-4206, Oct. 1980.
Chem. Abs. 71:3392f (1969).
Chem. Abs. 84:35211f (1976).

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