Amidinothioureas

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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260465D, 424322, 560 34, 564 47, 564 48, 564 49, 564 50, 564 52, 564 53, 564 54, 544160, 544390, 544402, C07C15709, A61K 3117

Patent

active

044182090

ABSTRACT:
This invention describes a new class of 1-amidino-3-phenylthiourea and N'-phenylamidinothiourea compounds wherein the phenyl group is ortho substituted, and processes for their preparation. The phenylamidinothiourea compounds may be incorporated into pharmaceutical preparations which are useful for producing anti-ulcerogenic, antisecretory, antispasmodic, antihypertensive, anti-arrhythmic, anesthetic, antidiarrheal and antiparasitic action.

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Ueda et al., Chem. Pharm. Bull. (1971), vol. 19, pp. 1990-1999.
Conant et al., "The Chemistry of Organic Compounds", 4th Ed. (1952), p. 335, Publ. MacMillan Co.
Curd et al., J. Chem. Soc. (1949), pp. 1732-1745.

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