Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1979-07-16
1980-12-16
Randolph, John D.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
546278, 546329, 546330, 546346, 548351, A61K 31415, C07D40102
Patent
active
042397642
ABSTRACT:
Compounds of the formula ##STR1## where Ar represents a radical selected from the group consisting of 2,6-dichlorophenyl, 2,5-dichlorophenyl, 2-chloro-6-methylphenyl, 2-chloro-4-methylphenyl, 2,6-dichloro-4-bromophenyl, 4-cyanophenyl, 2,5-dimethoxyphenyl, and 2-methyl-5-fluorophenyl, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as bradycardiacs.
REFERENCES:
patent: 3752810 (1973-08-01), Stahle et al.
patent: 3850926 (1974-11-01), Stahle et al.
Burger, Medicinal Chemistry, 2nd Ed., frontispage and pp. 79-81, Interscience Publishers, Inc. N. Y. 1960.
Hoefke Wolfgang
Koppe Herbert
Kummer Werner
Stahle Helmut
Boehringer Ingelheim GmbH
Randolph John D.
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