Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1979-05-31
1980-12-16
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544 22, 544 25, 544 28, 544 27, C07D50134
Patent
active
042397588
ABSTRACT:
A novel cephalosporin derivative of the formula: ##STR1## [wherein X is hydrogen, hydroxyl, acyloxy, alkoxy, carbamoyloxy, quaternary ammonium or a group of the formula --SR.sup.1 (where R.sup.1 is a nitrogen-containing heterocyclic group)] or a pharmaceutically acceptable salt or ester thereof is found to have potent antibiotic activity against various bacteria, particularly against gram-negative bacteria such as Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Proteus mirabilis, Proteus morganii, Proteus rettgeri and Citrobacter freundii.
REFERENCES:
patent: 4080498 (1978-03-01), Numata et al.
patent: 4098888 (1978-07-01), Ochiai et al.
patent: 4172891 (1979-10-01), Numata et al.
Minamida Isao
Nishimura Tatsuo
Numata Mitsuo
Shiraishi Mitsuru
Yamaoka Masayoshi
Rizzo Nicholas S.
Takeda Chemical Industries Ltd.
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