Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1984-06-18
1988-08-16
Robinson, Allen J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 31495
Patent
active
047643765
ABSTRACT:
This invention provides a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals by administering certain pyrazine derivatives. Pharmaceutical formulations of the pyrazine derivatives are also provided.
REFERENCES:
patent: 3544682 (1970-12-01), Taylor et al.
patent: 3928352 (1975-12-01), Taylor
Carter et al, Chemotherapy of Cancer, 2nd Ed. pp. 361, 364 and 365 (1981).
Hirsch Kenneth S.
Taylor Harold M.
Conrad Robert A.
Eli Lilly and Company
Robinson Allen J.
Whitaker Leroy
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