Process for the preparation of the crystalline monohydrate of 7-

Details Process for the preparation of the crystalline monohydrate of 7- Process for the preparation of the crystalline monohydrate of 7-

1979-05-21

1980-11-18

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D50102, C07D50112, C07D50122

Patent

active

042347211

ABSTRACT:
A novel crystalline monohydrate of 7-[D-.alpha.-amino-.alpha.-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4 -carboxylic acid is prepared and found to be a stable useful form of the cephalosporin antibiotic especially advantageous for pharmaceutical formulations.

REFERENCES:
patent: Re29164 (1977-03-01), Crast, Jr.
patent: 3489752 (1970-01-01), Crast, Jr.
patent: 3781282 (1973-12-01), Garbrecht
patent: 3957773 (1976-05-01), Burton et al.
patent: 3985741 (1976-10-01), Crast, Jr. et al.
Dunn et al. T. Antibiotics 24, 65-80 (1976).
Marconi et al. Chem Abs. 83, 145764a (1975).

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