Hydroxy-substituted cephalosporins

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

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Other Related Categories

424246, 544 24, 544 30, 544 16, C07D50136, C07D50120, A61K 31545

Type

Patent

Status

active

Patent number

040641228

Description

ABSTRACT:
Hydroxy-substituted cephalosporins, particularly 7-(.alpha.-hydroxy-arylacetamido)-3-substituted-3-cephem-4-carboxylic acids of the formula: ##STR1## wherein R is a hydrogen atom, an esterified carboxy or carboxy group, and Y is a lower alkanoyl, lower alkoxy or azido group or a group of the formula: --SR.sub.3 in which R.sub.3 is a heterocyclic residue. These compounds have antibacterial activity against Gram-positive and Gram-negative bacteria.

REFERENCES:
patent: 3855213 (1974-12-01), Dunn et al.

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