Process for the preparation of 2-halogeno-5-cyano pyridines

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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544124, 546193, 546281, 546286, C07D41304, C07D21309, C07D21384

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active

054592739

ABSTRACT:
The title compounds of the formula ##STR1## can be prepared by reacting methylene-glutaconic acid dinitriles of the formula

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Chemical Abstract; 27-Heterocycles, p. 639, vol. 103, 1985; CA#71193W: "2-Chloronicotinic acid", F. Nagy et al.
Chemical Abstract, p. 742, vol. 111, 1989; CA#57553x: "Preparation of .alpha.-halopyridine derivatives by photochemical halogenation", K. Suzuki et al.
Y. Hiroshi et al, "Site selectivity in the reaction of 3-substituted pyridine 1-oxides with phosphoryl chloride", Chem. Abstr. 192171r, V. 110, No. 21, (1989) p. 685.

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