Method for purifying secreted Mac-2-binding glycoprotein

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Glycoprotein – e.g. – mucins – proteoglycans – etc.

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

530396, 530412, 530416, 530417, 210635, 210656, 210660, C07K 100, B01D 1508

Patent

active

056440359

ABSTRACT:
A purified glycoprotein complex of over 1200 kD apparent native molecular weight having a sedimentation value of approximately 25S and having the ability to selectively bind human Mac-2 or interfere with PHA activation of lymphocytes, DNA sequences that encode the protein, and expression systems for expressing it, thus providing for medicaments that are useful for treating or diagnosing diseases, including cancer, infectious disease, and diseases of the immune system.

REFERENCES:
patent: 5169936 (1992-12-01), Staples et al.
patent: 5304636 (1994-04-01), Blaas et al.
Dupuis et al, Can. J. Biochem. Cell Biol., vol. 63, pp. 932-940, 1985.
Rosenberg et al, The Journal of Biological Chemistry, vol. 266, No. 28, pp. 18731-18736, Oct. 5, 1991.
Linsley et al, Biochemistry, vol. 25, No. 10, pp. 2978-2986, 1986.
Leagreid et al, Acta Paediatr. Scand., vol. 75, pp. 696-701, 1986.
Sharon et al, Science, vol. 246, pp. 227-234, 13 Oct., 1989.
Kodama et al, Nature, vol. 343, pp. 531-535, 8 Feb., 1990.
Woo et al, The Journal of Biological Chemistry, vol. 265, No. 13, pp. 7097-7099, May 5, 1990.
Iacobelli et al, FEBS, vol. 319, No. 1, 2, pp. 59-65, Mar. 1993.
Koths et al, The Journal of Biological Chemistry, vol. 268, No. 19, pp. 14245-14249, Jul. 5, 1993.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for purifying secreted Mac-2-binding glycoprotein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for purifying secreted Mac-2-binding glycoprotein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for purifying secreted Mac-2-binding glycoprotein will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-598576

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.