Phenyl alpha acyloxyalkanoic acids, derivatives and their therap

Details Phenyl alpha acyloxyalkanoic acids, derivatives and their therap Phenyl alpha acyloxyalkanoic acids, derivatives and their therap

1994-07-18

1997-07-01

Dodson, Shelley A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

424 59, 424 60, 424 701, 514529, 514532, 514546, 514548, 514553, 514557, 514568, A61K 31235, A61K 31225

Patent

active

056439490

ABSTRACT:
Therapeutic as well as preventative measures to improve the cosmetic conditions or to alleviate the symptoms of dermatologic disorders with phenyl alpha acyloxyalkanoic acids and derivatives is disclosed. The cosmetic conditions and dermatologic disorders in humans in which the compounds may be useful include brittle or soft nails; abnormally thin skin, mucous membranes or wound; friction blisters; brittle hairs; pruritus; acne; and diseased nails, skin or mucous membranes due to natural or unnatural causes including but not limited to inflammations or infections. The phenyl alpha acyloxyalkanoic acids and derivatives include, for example, diphenyl alpha acetoxyacetic acid, phenyl alpha acetoxyacetic acid, phenyl alpha methyl alpha acetoxyacetic acid and phenyl alpha acetoxypropanoic acid. The compositions containing the active ingredients are also useful for treatment of skin, nails and hair conditions or disorders in domestic animals.

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patent: 4105783 (1978-08-01), Yu et al.
patent: 4216224 (1990-08-01), Yu et al.
patent: 4246261 (1981-01-01), Van Scott et al.
patent: 4363815 (1982-12-01), Yu et al.
patent: 4518789 (1985-05-01), Yu et al.
patent: 5258391 (1993-11-01), Van Scott et al.

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