Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-07-02
1997-07-01
McKane, Joseph
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5142285, 5142342, 514256, 544 62, 544127, 544333, 546118, C07D47102, A61K 3144
Patent
active
056439229
ABSTRACT:
The present invention provides compounds of formula ##STR1## and the pharmaceutically acceptable salts thereof which are potent antagonists of PAF and are useful in the treatment of PAF-related disorders including asthma, rhinitis, shock, respiratory distress syndrome, acute inflammation, transplanted organ rejection, gastrointestinal ulceration, allergic skin diseases, delayed cellular immunity, parturition, fetal lung maturation, and cellular differentiation.
REFERENCES:
patent: 5180723 (1993-01-01), Whittaker et al.
patent: 5180724 (1993-01-01), Bowles et al.
patent: 5459152 (1995-10-01), Summers et al.
patent: 5486525 (1996-01-01), Summers, Jr. et al.
Davidsen Steven K.
Sheppard George S.
Summers James B.
Abbott Laboratories
Browder Monte R.
Martin Michael P.
McKane Joseph
Myers, Jr. Richard S.
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