High-affinity RNA ligands of basic fibroblast growth factor

Details High-affinity RNA ligands of basic fibroblast growth factor High-affinity RNA ligands of basic fibroblast growth factor

1994-02-10

1995-10-17

Zitomer, Stephanie W.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 935 77, 935 78, C12Q 168, C12P 1934

Patent

active

054590159

ABSTRACT:
Methods are described for the identification and preparation of nucleic acid ligands and ligand solutions to basic fibroblast growth factor (bFGF). Included in the invention are nucleic acid ligands to bFGF which are inhibitors of bFGF and 2'-amino-modified RNA ligands to bFGF.

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