HU-B1.219, a novel human hematopoietin receptor

Details HU-B1.219, a novel human hematopoietin receptor HU-B1.219, a novel human hematopoietin receptor

1994-09-14

1997-07-01

Ulm, John

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 697, 4352523, 4353201, 530350, 536 234, 536 235, C07K 14705, C12N 510, C12N 1517

Patent

active

056437480

ABSTRACT:
The present invention relates to a novel member of the hematopoietin receptor family, herein referred to as Hu-B1.219. In particular, the invention relates to nucleotide sequences and expression vectors encoding Hu-B1.219 gene product. Genetically engineered host cells that express the Hu-B1.219 coding sequence may be used to evaluate and screen for ligands or drugs involved in Hu-B1.219 interaction and regulation. Since Hu-B1.219 expression has been detected in certain human fetal tissues and cancer cells, molecular probes designed from its nucleotide sequence may be useful for prenatal testing and cancer diagnosis.

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