Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1994-03-21
1997-07-01
Chambers, Jasemine C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 435366, 435371, 4353723, 935 62, 935 34, 935 70, 536 231, C12N 1563, C12N 1579, C12N 1509
Patent
active
056437463
ABSTRACT:
The present invention relates to promoter elements from human type I transglutaminase (TGase I) genes for controlled gene expression of both human TGase I and heterologous proteins. These promoter elements permit tissue-specific expression of genes, e.g. for use in human gene therapy and for testing pharmaceutical agents with artificial skin. Additionally, the subject promoter elements can provide differential regulation under physiological conditions or in the presence of exogenously added factors including calcium and retinoic acid.
REFERENCES:
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Goldsmith Lowell Alan
Polakowska Renata Regina
Chambers Jasemine C.
Hauda Karen M.
Research Corporation Technologies Inc.
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